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TIGeR: Translational implementation of genomics for rare diseases

Alberta patients with or suspected of having rare genetic diseases continue to face lengthy diagnostic odysseys, and clinical genome wide sequencing has emerged as a rapid and cost-effective approach to diagnosis. Large scale clinical genomics are not available in Alberta, and Alberta Precision Laboratories (APL) has relied primarily on US commercial labs to provide clinical […]

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Field validation of technologies for anaerobic benzene and alkylbenzene bioremediation

The federal contaminated sites inventory lists over 1000 soil and groundwater sites contaminated with BTEX compounds (Benzene, Toluene, Ethylbenzene, and Xylenes). BTEX present significant risks to human and environmental health, especially benzene, a known carcinogen. Benzene is also particularly challenging to remediate due to its slow biodegradation in the absence of oxygen. Genomics-based modeling of

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Validation and integration of genomics solutions for offshore oil exploration in Nova Scotia and beyond

Given the competitiveness among the super-majors to find and develop new oil and gas reservoirs around the world, and the billion-dollar cost of exploration programs, any proven enhancements in offshore exploration success will have an immediate economic return. This project focuses on de-risking exploration and development in offshore Nova Scotia by the validation and integration

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Summer Internship for Indigenous Peoples in Genomics (SING)

Low Indigenous representation across the genome sciences, ethics, and science policy fields is an ongoing problem. For one full week each summer, a University of Alberta developed initiative called Summer internship for Indigenous peoples in Genomics (SING) Canada, attacks these problems head on and via diverse themes. The annual SING summer program is all-expenses-paid, including

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The Metabolomics Innovation Centre (TMIC)

The Metabolomics Innovation Centre (TMIC) is Canada’s national metabolomics** laboratory, mandated to provide Canadian companies, scientists and trainees with access to comprehensive, cutting-edge metabolomic services and technologies. Originally launched in 2011 as a Genome Canada Science and Technology Innovation Centre, TMIC has received multiple renewed mandates to continue to grow and advance metabolomics as a

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The Canadian BioGenome Project

The richness of Canada’s biodiversity is under threat today due to climate change, habitat destruction and novel emerging diseases. A common thread across conservation strategies is the need for genomic tools to address knowledge gaps related to species evolution, adaption, viability, and genetic diversity. A reference-quality whole genome sequence is the foundation for such genetic

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Application of genomics to enhance wetland treatment systems for remediation of processed water in northern environments

Constructed wetland treatment systems (CWTS) are one of very few scalable and cost-effective technologies for remediating large volumes of wastewaters. An in-depth understanding of how these nature-based, passive, low energy systems operate to treat industrial waste is needed to enhance treatment efficacy in cold weather, particularly in northern environments that are challenged by short summers

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TRIA-FoR: Transformative risk assessment and forest resilience using genomic tools for the Mountain Pine Beetle outbreak

Over the past two decades, mountain pine beetle (MPB) has killed more than 20 M hectares of mainly lodgepole pine forests in western Canada. In the wake of this MPB epidemic, decision makers seek reforestation strategies that increase forest resiliency to future outbreaks. Simultaneously, the uncertain risk that MPB poses to jack pine challenges decision

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Genomic ASSETS (Antimicrobial Stewardship Systems from Evidence-based Treatment Strategies) for livestock

Disease-causing bacteria are increasingly able to resist antibiotics used for treatment creating an unprecedented and growing global threat to human and animal health. Animal agriculture is also facing world-wide pressure to reduce its use of antibiotics in food animals. To meet this challenge veterinarians and livestock producers need fast and precise information about disease in

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Integrating genomic approaches to improve dairy cattle resilience: A comprehensive goal to enhance Canadian dairy industry sustainability

Dairy is one of Canada’s most important and dynamic industries. Global demand for dairy products is set to expand further in concert with the middle-class of emerging economies, the need for safe, affordable, nutritious and high-quality milk protein in developing countries and world population expansion. At the same time, the dairy industry is also facing

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