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Cardiotoxicity Prevention Research Initiative (CAPRI) Phase 1 – Registry

Living with cancer longer is possible due to better cancer treatments but these treatments can damage the cardiovascular system. This can happen in up to 15-20% of people receiving treatment for breast and other aggressive cancers. The purpose of this project is to develop a state-of-the-art database system, called the CArdiotoxicity Prevention Research Investigation (CAPRI). […]

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Solve-RD Alberta: A precision health ecosystem for rare diseases

Precision Health is an emerging paradigm that promises to improve the health of Albertans by considering each patient’s unique genomic, environmental and lifestyle characteristics to create personalized prevention and treatment plans. To realize the full potential of precision health, newer methods of integrating high quality clinical information with genomic data and methods to improve sharing

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Alberta Precision Health Initiative for Arthritis and Complex Immune Diseases

Unchecked inflammation underlies complex immune-mediated conditions, including arthritis, resulting in significant morbidity and high costs. This project aims to overcome the barriers to integrate precision health data and accelerate its translation and application into practice in the context of inflammatory arthritis. Precision Health requires standardized data collection and integration including clinical, environmental, biologic, and administrative

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GE3LS network in genomics and personalized health

The GAPH Network brings together GE3LS (the Genomics and its ethical, environmental, economic, legal, and social aspects) components of the 17 projects funded through Genome Canada’s Genomics and Personalized Health programme (GAPH), with the objectives of: sharing best practices, improving and priming future collaborative research endeavours, accelerating the progress to market of GAPH technologies, and

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PEGASUS: Personalized genomics for prenatal aneuploidy screening using maternal blood

Recently it was identified that during pregnancy, there is fetal DNA in maternal blood in sufficient quantities to be analysed and methods have been proposed to detect the presence or not of a fetus with Down syndrome using maternal blood. The introduction of genomic blood testing as proposed in the context of this project could

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Reducing stroke burden with hospital-ready biomarker test for rapid TIA triage

The SpecTRA project (Spectrometry for TIA Rapid Assessment) is an emergency medicine and neurology project designed to reduce the occurrence of stroke through early detection of early warning signs. Stroke accounts for the greatest use of acute and chronic care beds in Canada, with large economic and social costs associated with treatment and rehabilitation. The

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PACE-‘Omics: Personalized, accessible, cost-effective applications of ‘Omics technologies

The goal of personalized medicine (PM) is to tailor medical treatments and services to the biological makeup of individual patients. This project provides a way to maximize investments made in PM technology to secure patient benefits, lower health care costs, and waste fewer resources. It does so by bridging informational gaps between PM researchers, developers,

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Modeling and therapeutic targeting of the clinical and genetic diversity of glioblastoma

Glioblastoma (GBM) is a deadly brain cancer that has eluded major treatment advances. Previous research methodology of growing stem cells from the brain was pioneered by a lead on this project out of the University of Calgary and a recently established cell-based model system provided this project with the foundation for an innovative drug discovery

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