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Solve-RD Alberta: A precision health ecosystem for rare diseases

Precision Health is an emerging paradigm that promises to improve the health of Albertans by considering each patient’s unique genomic, environmental and lifestyle characteristics to create personalized prevention and treatment plans. To realize the full potential of precision health, newer methods of integrating high quality clinical information with genomic data and methods to improve sharing […]

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Alberta Precision Health Initiative for Arthritis and Complex Immune Diseases

Unchecked inflammation underlies complex immune-mediated conditions, including arthritis, resulting in significant morbidity and high costs. This project aims to overcome the barriers to integrate precision health data and accelerate its translation and application into practice in the context of inflammatory arthritis. Precision Health requires standardized data collection and integration including clinical, environmental, biologic, and administrative

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Establishing a metabolomics technology demonstration centre

Metabolomics is an emerging field of omics science that measures thousands of small molecule metabolites in cells, tissues, and organisms. The Metabolomics Innovation Centre (TMIC) is Canada’s national platform for large-scale metabolomics research and technology development and has created novel metabolomic technologies for a wide range of applications, including human and animal health, agriculture, and

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Microbial genomics for derisking offshore oil and gas exploration in Nova Scotia

The proposed GAPP project fits within a broad initiative in offshore oil and gas exploration geoscience mapping led by the Nova Scotia Department of Energy (NSDoE), the project’s End User. The province has partnered with this team to develop, validate, and deploy three new genomics-based bioassay tools for offshore prospecting on the Scotian Slope. Results

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Application of genomics for increasing seed oil content in soybean

The global market for soybean seed sales is estimated at $3.0 – $4.5 billion. Arcadia Biosciences estimates that superior soybean varieties carrying the enhanced seed oil trait could capture up to 25% of this market. Revenues would be obtained through licensing the trait or the resulting varieties to one or more partners with potential for

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Development of a new generation of modified live virus vaccine for PEDV using reverse genetics system

Porcine epidemic diarrhea virus (PEDV) is an infectious and highly contagious swine virus. Recently, outbreaks of severe PED disease have been reported in the USA and Canada. The goal of this project is to develop a live virus vaccine specifically directed towards sows to protect suckling piglets against disease. Despite long-term efforts, effective vaccines to

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Enhanced molecular diagnostics and validating genetic resistance to PEDv in pigs

After ravaging Asia for over a decade, Porcine Epidemic Diarrhea Virus (PEDV) entered USA in April 2013, and Canada in January 2014. Controlling the spread of PEDV by surveillance and biosecurity measures and eliminating the virus from infected farms are industry priorities. This project will investigate genomic and molecular mechanisms associated with PEDV survivorship in

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The use of new molecules in association with real-time qPCR assays to discriminate infectious from non-infectious porcine epidemic diarrhea virus (PEDv) particles

Porcine epidemic diarrhea virus (PEDV) is the causative agent of porcine epidemic diarrhea resulting in high mortality in affected swine, particularly neonatal piglets, characterize PED disease. This emerging virus rapidly spreads and has caused significant economic losses, primarily due to very high mortality (50% to 100%) of young piglets in affected herds. The aim of

The use of new molecules in association with real-time qPCR assays to discriminate infectious from non-infectious porcine epidemic diarrhea virus (PEDv) particles Read More »

Improving Canadian pork industry profits and export potential by developing genomic tools to enhance health, performance, and disease resilience in wean to finish pigs

The existence of considerable host genetic variance in susceptibility to diseases is well documented in the pig, and currently, discussion and research has focused on improving pig health and the most appropriate means to do this. Thus, the goal of this project is to develop genomic tools for genetic improvement of disease resilience in the

Improving Canadian pork industry profits and export potential by developing genomic tools to enhance health, performance, and disease resilience in wean to finish pigs Read More »

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