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BioNet Alberta

In response to stakeholder consultations across the province, recommendations from post-secondary institutions, and support from the broader research and end-user community, Genome Alberta developed BioNet Alberta for Genome Canada’s Regional Priorities Partnership Program (RP3). BioNet Alberta is a diverse network-based approach to building provincial capacity in the area of bioinformatics and computational biology (B/CB). The […]

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Application of genomics-based tools to select for pig disease resilience

Disease is an economically important trait in Canadian pork production and is one of the most difficult challenges to manage. It also contributes to poor public perception of food animal production in terms of animal welfare, food safety, and antimicrobial resistance. Pig breeding companies (Users) represented by PigGen Canada are the foundation of the Canadian

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Field validation of technologies for anaerobic benzene and alkylbenzene bioremediation

The federal contaminated sites inventory lists over 1000 soil and groundwater sites contaminated with BTEX compounds (Benzene, Toluene, Ethylbenzene, and Xylenes). BTEX present significant risks to human and environmental health, especially benzene, a known carcinogen. Benzene is also particularly challenging to remediate due to its slow biodegradation in the absence of oxygen. Genomics-based modeling of

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Validation and integration of genomics solutions for offshore oil exploration in Nova Scotia and beyond

Given the competitiveness among the super-majors to find and develop new oil and gas reservoirs around the world, and the billion-dollar cost of exploration programs, any proven enhancements in offshore exploration success will have an immediate economic return. This project focuses on de-risking exploration and development in offshore Nova Scotia by the validation and integration

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Pegasus 2 – Personalized genomics for prenatal abnormalities screening using maternal blood: Towards first tier screening and beyond

Non-invasive prenatal screening (NIPS) genomics analysis of cell free DNA in maternal blood has the potential to perform well as a first-tier screening test for aneuploidies. NIPS use as a first-tier screening test would simplify, streamline, and enhance the safety of prenatal screening for fetal aneuploidies and could potentially detect other important fetal abnormalities. However,

Pegasus 2 – Personalized genomics for prenatal abnormalities screening using maternal blood: Towards first tier screening and beyond Read More »

Harnessing multi-omics to deliver innovative diagnostic care for rare genetic diseases in Canada (C4R-SOLVE)

There are about 7,000 rare genetic diseases (RDs) that affect more than one million Canadians. RDs have a devastating impact on Canadians: two-thirds cause significant disability, three-quarters affect children, more than half lead to early death, and almost all have no treatment. The cause of more than one-third of the 7000 RDs is currently unknown.

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Reducing the global burden of infectious diseases through precision population health

The global rise in the prevalence of antibiotic resistant bacteria is a serious problem, threatening all modern medicine. A primary reason is the one-size-fits-all approach to treating infections, which encourages overuse of drugs and results in unnecessary sickness and death. To address this problem, this project is using metabolomics to create an automated analytical system

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Genomic approaches to the control of Bovine Respiratory Disease Complex

The bovine respiratory disease (BRD) is an important cause of morbidity and mortality in beef cattle, causing considerable economic losses. This project explores the role of host genetics in shaping the composition of the microbiome, which is crucial in determining health and disease in ruminants. Here the team will characterize the genomic and metabolic markers,

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