While everyone is battling the current pandemic, superbugs are expanding another battlefield. Here is how bioinformatics is improving our odds for survival
Miracles only occur in the darkest hours and heroes are only born from the most tragic of horrors. Here’s how the fastest transition in history from pandemic to vaccines happened.
Curing or treating diseases may rely more on cancelling gene expression and “disease expression,” than gene editing, although many future treatments are likely to combine genetic techniques.
Researchers find the flu shot may protect against Covid-19 too. Meanwhile, decoding cell-surface sugars presents a major breakthrough in the fight against infections of all types.
Researchers sequenced the genome of Alexander Fleming’s original penicillin mold and compared it to later versions. What they found may be the answer to antibiotic-resistant microbes.
Remake of cell line development delivers a major production boost for CHO cell protein factories
Researchers find human gut microbiomes create tendency for disease susceptibility or resistance, above and beyond other factors such as poverty and general health conditions.
Today's word: Phylogeny
Genomics reveal more than contact tracing alone, such as whether a healthcare worker contracted SARS-CoV-2 from a patient or a social gathering.
Viral family trees
Researchers identify 29 FDA-approved drugs, 12 drugs in clinical trials, and 28 preclinical compounds that can be repurposed to fight COVID-19
Traditional vaccine research took 10-15 years, now researchers hope bioinformatics will condense that to less than 2 years
COVIDathon combines the talents and tools of diverse disciplines from around the world in a single collaborative effort to defeat the worst pandemic in modern times
Is it a natural occurring virus or a bioweapon? Bioinformatics can potentially reveal origin and treatment of coronaviruses.
U.S. now requires pharmacogenomics data be included on drug labels. Other countries expected to do the same. The new drug info speeds personalized treatments to patients with preemptive pharmacogenomics tests in their EMRs.
Using the newly created bioinformatics tool, MHcut, with commercial genome-editing technology, enables researchers to model diseases without the need of patient samples. This combination will make it much easier to study diseases even when patients are rare or unavailable.
It's going to involve a lot of math
"If you do experiments, it could take 20 or 30 years to figure it out. With this software system, you can do it in five minutes.”
AI maps and analyzes cellular response to disease and treatments in computational models that go far beyond experimentally available data.
There are some questions too big for even AI on conventional computers to answer within the lifetime of the universe.
Bioinformatics is the key to unlocking the mysteries of nature, finding life-saving cures, and bringing a new age to medicine beyond anything previously imagined.