Health
Building the Metabolomics Toolbox: Enabling Rapid Disease Diagnosis Through Metabolic Profiling
Metabolomics, or metabolic profiling, is an emerging branch of genetic research. It uses small molecules called metabolites to detect changes in cell behavior and organ function. It also uses these chemicals to monitor and measure the larger-scale physiological changes that occur in response to subtle changes in the environment, thus helping to improve our monitoring of adverse drug reactions and better understand individual sensitivities to prescription drugs. Read more
Diagnostic Applications of Microarrays in Organ Transplantation
Approximately 200,000 people in the USA and Canada are alive today because of organ transplants. However, despite recent progress in organ transplantation, the immune response to foreign tissue remains an obstacle to success. Powerful drugs are needed to prevent rejection. Also, better methods of detecting and measuring rejection are needed. The goal of the Diagnostic Applications of Microarrays in Organ Transplantation project is to develop tests that can determine when rejection is present and when it is not, so that patients can be managed more effectively, with fewer side effects. Read more
North American Conditional Mouse Mutagenesis
This project is led in Canada from the Universities of Manitoba and Toronto, with local participation by Drs. Derrick Rancourt and Edna Einsiedel at the University of Calgary (value of $600K). Read more