2012 Large-Scale Applied Research Project Competition 

Genome
Genomics and Personalized Health 

Criteria for Evaluating Pre-Applications 

 

Eligibility Criteria 

 

Each pre-application will be reviewed for eligibility. The following criteria will be used. 

 

Does the proposal: 

. respond to the objectives of the Genome Canada competition as 
described in the RFA; 


. include genomics approaches as essential components in terms of 
importance to the overall outcomes of the project; 
. address personalized health in humans; and, 
. possess a scale and scope such that it is able to address challenges 
requiring a genomics approach, be internationally competitive and 
have potential to have a major impact? 




 

If considered eligible, the pre-application will be reviewed using the criteria described 
below. 

 

Review Criteria 

 

There are two main areas of evaluation that will be scored: 

 

. Research Proposal 
. Socio-Economic Benefits for Canada 


 

In addition, reviewers will be asked to comment on the Management and Financial 
aspects of the pre-application. 

 

1. Research Proposal 


 

Including Research on Ethical, Environmental, Economic, Legal and Social 
Aspects of Genomics (GE3LS) 

 

. Research Context and Originality 


 

o To what extent does the proposed research lead, extend and/or 
complement national and international work in the area? 




 

o To what extent does the proposed research reflect creative, original 
thinking? 





. Research Plans 


 

o How appropriate is the proposed approach given the objectives of the 
outlined research? 
o How feasible is the research given the projected resources and time-
lines? 
o If the main focus of the research project is genomics, does the 
integrated GE3LS investigation address salient aspects of the 
genomics project and are the research questions directly related to 
the objectives and expected outcomes? 




 

. Research Expertise 


 

o How appropriate is the expertise of the research team in terms of 
realizing the research goals? 




 

2. Socio-Economic Benefits for Canada 


 

. Deliverables 
o To what extent have the applicants identified appropriate deliverables 
in terms of their potential to have clinical utility and/or practical 
applicability? 




 

o What is the probability that the deliverables will be achieved by the 
end of the funding period? 




 

. Expected Benefits 


 

o How significant are the anticipated benefits described in the proposal 
in terms of their potential of contributing to a more evidence-based 
approach to health and improved cost-effectiveness of the health-
care system? 




 

. Strategy for Realizing Benefits 


 

o How persuasive is the strategy set out by the applicants for realizing 
benefits from their research? 




 

o How appropriate is the expertise for implementing a strategy to 
realize benefits? 




 

o To what extent are likely end-users involved in the project and the 
strategy to realize benefits? 




 

o Will the benefits be realized within a short time-frame after the end of 
the project? 




 


Note: All else being equal between two proposals, the one which makes a 
stronger case for benefits to be achieved sooner will be assessed more 
favourably. 

 

 

3. Management and Financial Criteria 
. Management 


 

o How appropriate is the proposed management plan? 




 

o What is the potential for the team to be able to make critical decisions 
regarding the overall research direction? 




 

o To what extent does the team have the expertise for managing large-
scale projects that involve research and the application of results? 




 

. Financial 


 

o Do the budgeted costs meet the definition of Eligible Costs (see 
Section 7.1, Guidelines for Funding Large-Scale Genomics Research 
Projects, December 2011)? 




 

o Are the budgeted costs aligned with the proposed research plan? 




 

o Are the budgeted costs reasonable relative to the research to be 
conducted, the methodologies used, and the deliverables expected ? 




 

o Does the proposed co-funding comply with the guidelines for Eligible 
Co-funding (see Section 7.2, Guidelines for Funding Large-Scale 
Genomics Research Projects)? 




 

o Is the proposed co-funding plan feasible, that is, what is the likelihood 
of the project being able to secure at least 75% of the co-funding for 
eligible costs at the time of the release of funds?